These runes were added into Diablo I through the Hellfire expansion set. They were single use items, similar to a scroll, but were placed on the ground like a trap.
“ Effect: Casts a fireball/Creates a one-square fire flame. Requirement: None. Quality level: 1...Rune of Fire
“ Effect: Casts Immolation Requirement: 42 Magic Quality level: 7 Cost: 400 gold Hellfire Runes...Greater Rune of Fire
“ Effect: Casts Lightning Wall Requirement: 13 Magic Quality level: 3 Cost: 200 gold Hellfire...Rune of Lightning
“ Effect: Casts Nova Requirement: 42 Magic Quality level: 7 Cost: 500 gold Hellfire Runes Rune of...Greater Rune of Lightning