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The skulls of some demonic creatures, inscribed with eldritch symbols, are said to work much like gems.

Weapons: Adds Mana and Life Steal to attack
Shields: Adds attacker takes damage
Helms and Body Armor: Adds Mana and Life regeneration

Gem Level Weapons Shield Helms/Body Armor
Chipped
Chipped Skull
1 Steals 2% life, 1% Mana Attacker Takes 4 Damage Replenish Life +2, Regenerate Mana 8%
Flawed
Flawed Skull
5 Steals 2% life, 2% Mana Attacker Takes 8 Damage Replenish Life +3, Regenerate Mana 8%
Normal
Skull
12 Steals 3% life, 2% Mana Attacker Takes 12 Damage Replenish Life +3, Regenerate Mana 12%
Flawless
Flawless Skull
15 Steals 3% life, 3% Mana Attacker Takes 16 Damage Replenish Life +4, Regenerate Mana 12%
Perfect
Perfect Skull
18 Steals 4% life, 3% Mana Attacker Takes 20 Damage Replenish Life +5, Regenerate Mana 19%
Diablo IIFlawlessamethyst AmethystFlawlessdiamond DiamondFlawlessemerald EmeraldFlawlessruby RubyFlawlesssaphire SapphireFlawlesstopaz TopazFlawlessskull Skull

Diablo IIIMarquise Amethyst AmethystMarquise Diamond DiamondMarquise Emerald EmeraldMarquise Ruby RubyMarquise Topaz TopazIceblink (Diablo III) Legendary
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