This is a semi-rare rune which can be inserted into Socketed Items. Requires level 35 to use. In Single Player, Open, and Ladder, transmuting three Io Runes and a Flawed Topaz in the Horadric Cube yields a Lum Rune.
- Weapons: +10 To Vitality
- Armor: +10 To Vitality
- Helms: +10 To Vitality
- Shield: +10 To Vitality
The Io rune is used in the following Rune Words:
Used in Recipes Edit
- Dropped by The Countess on Nightmare difficulty or higher.
- 3 Hel Runes + 1 Chipped Diamond.
- It is possible to receive as low a rune as Io from the Mephisto's Soulstone quest in Hell difficulty, and as high as or higher than Io (e.g. Ko Rune) in Nightmare difficulty.
- Prior to Patch 1.09, Io Runes were called Po.
|Diablo II Runes|
| El • Eld • Tir • Nef • Eth • Ith • Tal • Ral • Ort • Thul • Amn • Sol • Shael • Dol • Hel • Io • Lum • Ko • Fal |
Lem • Pul • Um • Mal • Ist • Gul
Vex • Ohm • Lo • Sur • Ber • Jah • Cham • Zod