During the Eternal Conflict, Diablo gave Iskatu the Pandemonium Loop, hoping to sow fear amongst the angels guarding the Pandemonium Fortress. Iskatu used it to great effect. However, its power could not sway Imperius, who cut off Iskatu's arm (causing the ring to be lost) before the demon fled the field of battle.
Aeons later, Iskatu was amongst the demons Diablo called to his side as he stormed the High Heavens. Diablo ordered Iskatu to ambush the Nephalem in the Vestibule of Light. However, he was again defeated.
Once a hero reaches a high enough level, however, Iskatu will possess desecration capabilities, which he casts with greatly reduced cooldown. To make the player run faster, Meteors (similar to those launched by Morlu Incinerators) fall onto the arena every few seconds. Each Meteor releases several Shadows too.
Abilities that can be used on multiple enemies at once is essential to surviving this fight. Iskatu himself isn't all that tough without his minions backing him, and should go down easily once you've polished off his Shadow Vermin. Beware of his deadly melee attack, though, which is combined with vanishing power, teleportation and healing debuff. A warning players will want to consider is that the debuff Iskatu (as well as all other Terror Demons) inflicts on a successful hit will reduce the effectiveness of all sources of healing. Players dependent on life regen may want to tread carefully, or risk death. Life per Kill helps a lot in this battle, though, for you will have to massacre Shadow Vermins anyway.
- "I do not fear you, nephalem. You'll find only death in this eternal realm."
- "The armies of hell will trample your corpses - the shades will devour your souls!
- "You believe you can defeat me, mortal? Our armies are ENDLESS!"