Orb may refer to:
- Sorceress Orbs, a type of weapon that can only be used by a Sorceress
- Ghostly Orb, a type of Monster Spawner
- Health Globes and Power Globes, drop from monsters to restore health or apply Nephalem Glory buffs (used to be called Orbs).
- Sources, a Wizard-only offhand item type.
- Life and Mana are displayed as orbs, as well as other class resources (Fury, Spirit, Wrath, Arcane Power, Hatred and Discipline)