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The Sin Lieutenants helped Azmodan gain dominance over the Burning Hells. During the End of Days, the lieutenants were present when Azmodan confronted Leah in a vision, staring menacingly at her. Some of them participated in the Army of Sin's siege on Bastion's Keep but were soon defeated by Tyrael and the Nephalem.
- Snitchley (also Greed)
- Bholen (Sloth)
- Zelusa the Grasping (Envy)
- Zaboul (Wrath)
- unknown (Pride)
- The aforementioned Lieutenants appear to correspond to the Cardinal sins in Church doctrine.