Besides its high Defense and boost to Skills, the main purpose of Skullder's Ire is its growing Magic Find, which at high levels can be very high and are the best in the game (this can be further augmented by socketing it with an Ist Rune or a Topaz). As it sports a self-repairing affix, a player lucky enough to find an Ethereal Skullder's Ire can make good use out of it and benefit from its extra high defense.
Required Level: 42
Required Strength: 97
+160-200% Enhanced Defense
Repairs 1 Durability In 5 Seconds
+ (1.25 Per Character Level) 1-123 % Better Chance Of Getting Magic Items (Based On Character Level)
+1 To All Skill Levels
Magic Damage Reduced By 10