The Tree of Inifuss is an ancient tree standing in the middle of the Dark Wood in Act I of Diablo II. It holds many mystical properties, such as the key to unlock the magical Cairn Stones. The Tree is guarded by Treehead Woodfist and his minions, a fierce Brute that does anything to prevent players from reaching the sacred Tree.
Reaching the Tree is needed for the quest Search for Cain. Players need to obtain the Scroll of Inifuss, the rune-inscribed bark of the Tree. Akara will then proceed to translate the runes so that players can unlock the Cairn Stones.